Science Magazine Webinar: Moving Stem Cell Research Forward: The Need for Standardization and Automation

Speakers:

Ronald D.G. McKay, Ph.D., National Institutes of Health, Bethesda, MD
Amy Wagers, Ph.D., Harvard University, Boston, MA
Mark D. Noble, Ph.D., University of Rochester Medical Center, Rochester, NY

Stem cell research has the potential to significantly impact a broad range of life science endeavors, ranging from improved drug discovery processes to revolutionary new therapeutics. The ability to control differentiation of stem cells into specialized cell types with high yield and precision is a key success factor that will determine the ultimate utility of such research. However, researchers are facing significant challenges in these efforts because stem cells are difficult to handle and there are very few automated or standardized tools available in this relatively new field. In this hour, we will hear from three panelists on the need for, and progress towards, a new level of standardization and automation in the management and handling of stem cell cultures and their differentiated progeny.
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GEN Magazine Webinar: Shifting Cell-Line Development into High Gear

Speakers:

Richard Visconti, Senior Research Biologist, In Vitro Sciences, Cell Production Group, Merck & Co.
Darren Cawkill, Ph.D., Senior Principal Scientist, Pfizer Global Research and Development
Fredrik Kamme, Ph.D., Senior Scientist, Applications Development, Cyntellect

Many scientists depend on stably transfected cell lines for cell-based compound-screening applications. However, in the process of developing novel assays for high-throughput screening, creating the appropriate cell line usually turns out to be the main bottleneck. The current economic environment, within which the pharmaceutical industry finds itself, calls for a better approach to cell-line development. Slow, manual, and iterative procedures need to be replaced by faster and automated systems that offer more efficiency and predictability.
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Standardizing Stem Cell Cultures to Maximize Differentiation Potential

Speaker:

Kristi Hohenstein, PhD.
Cyntellect

Derivation and propagation of embryonic and induced pluripotent stem cell (ESC/iPSC) lines are common tasks in stem cell biology, yet typical procedures vary extensively among laboratories. Manual methods are generally preferred because they result in consistent stem cell cultures, whereas enzymatic techniques are more widely used due to their scalability, but at the expense of reproducibility. To address these challenges, Cyntellect has developed innovative stem cell applications using the LEAP™ cell processing Workstation.
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Science Magazine Webinar: Advancing Cell Biology: Understanding the Cell Through New Tecnologies

Speakers:

James F. Leary, Ph.D., Purdue University, West Lafayette, IN
Marcie Glicksman, Ph.D., Harvard Center for Neurodiscovery, Boston, MA
Lars J. Brandén, Ph.D., Director Center for High Throughput Cell Biology, Yale University, CT

In recent years, cell biology has enjoyed rapid growth and has gained critical attention in academia and industry. Advances in cellular analysis technologies such as microscopy, cytometry, and high content analysis are having profound effects on the fields of stem cells, cancer research, immunology, and drug discovery.
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